Two-Phase Inpatient Withdrawal Programme for Long-Term Opioid Use in Non-Cancer Pain.

ABSTRACT:

Background

High-dose long-term opioid treatment for chronic non-cancer pain (CNCP) has become an increasing burden in industrialised countries. Opioid tapering and withdrawal in patients with CNCP remain challenging. This study evaluated a two-phase inpatient opioid withdrawal (OW) programme aimed at safely discontinuing opioid use in CNCP patients.

Methods

This prospective observational study was conducted from 2018 to 2023 at a Swiss tertiary care centre, involving CNCP patients on long-term opioid therapy (≥ 6 months, ≥ 100 mg morphine equivalent daily dose) who had failed outpatient withdrawal attempts. The programme consisted of a withdrawal phase (Phase 1) followed by multimodal pain rehabilitation (Phase 2). Outcomes included the proportion of patients opioid-free aft

SUBMITTER: Streitberger K 

PROVIDER: S-EPMC11926771 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature