Grey matter volume differences in pediatric obsessive-compulsive disorder: a meta-analysis of voxel-based morphometry studies.

ABSTRACT:

Background

Obsessive-compulsive disorder (OCD) is one of the most commonly seen mental disorders onset from childhood. The neural mechanisms underlying OCD development and maintenance remain poorly understood. Various empirical evidence from structural magnetic resonance imaging (MRI) studies has reported structural differences in grey matter (GM) among pediatric OCD patients. However, some of the findings diverge from others, and the association between GM and individual differences in pediatric OCD remains inconclusive. To address this gap, we conducted a meta-analysis to synthesize findings quantitatively.

Methods

The current research conducted a quantitative meta-analysis of voxel-based GM studies to elucidate existence of neural correlates in pediatric OCD. A whole brai

SUBMITTER: Li L 

PROVIDER: S-EPMC11927120 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature