Establishment and validation of a DIP panel for forensic ancestry inference and personal identification.

ABSTRACT:

Background

Biallelic Deletion/Insertion polymorphisms (DIPs), known for their significant diversity across various populations, serve as valuable markers for forensic ancestry inference and personal identification. In this study, we utilized DIPs to provide a potentially powerful forensic examination tool specifically tailored for East Asian populations. Our focus on ancestry allows us to delve deeper into the genetic signatures that characterize this diverse group, offering enhanced resolution in forensic analyses.

Methods

A total of 56 autosomal DIPs, 3 Y-chromosome DIPs, and the Amelogenin were selected to build the 60-panel. Population genetic parameters, principal component analysis (PCA), STRUCTURE analysis, and phylogenetic tree construction were employed to evaluate

SUBMITTER: Li S 

PROVIDER: S-EPMC11927128 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature