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ABSTRACT: Purpose
To investigate changes in the crystalline lens before and after the onset of myopia.Methods
This prospective cohort study was conducted in Guangzhou, Guangdong, China. Participants were initially emmetropic or hyperopic at baseline and were followed for 5 years, during which they were categorized into two groups: those who developed myopia (newly developed myopes [NDM]; n = 1669) and those who remained hyperopic or emmetropic (persistent nonmyopes [PNM]; n = 4259). Changes in spherical equivalent refraction (SER), axial length, lens thickness, and lens power were analyzed from 5 years before to 4 years after myopia onset. Age-related trends in SER and biometric parameters were compared between the PNM and NDM groups.Results
The mean age of the included child
SUBMITTER: Zhang J
PROVIDER: S-EPMC11927298 | biostudies-literature | 2025 Mar
REPOSITORIES: biostudies-literature