Liberation from mechanical ventilation using Extubation Advisor Decision Support (LEADS): protocol for a multicentre pilot trial.

ABSTRACT:

Introduction

Timely successful liberation from invasive ventilation has the potential to minimise critically ill patients' exposure to invasive ventilation, save costs and improve outcomes; yet no trials have evaluated strategies to better inform extubation decision-making. The Liberation from mechanical ventilation using Extubation Advisor (EA) Decision Support (LEADS) Pilot Trial will assess the feasibility of a trial of a novel extubation decision support tool on feasibility metrics. The primary feasibility outcome will reflect our ability to recruit the desired population. Secondary feasibility outcomes will assess rates of (1) consent, (2) randomisation, (3) intervention adherence, (4) bidirectional crossovers and the (5) completeness of clinical outcomes collected. We will al

SUBMITTER: Burns KEA 

PROVIDER: S-EPMC11927467 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature