The role of intraductal ultrasound in endoscopic biliary brushing for sampling in patients with malignant biliary strictures: a bicentric retrospective study.

ABSTRACT:

Background

Endoscopic biliary brushing is the first line modality for sampling in patients with indeterminate biliary stricture (BS); however, its sensitivity is limited. Endoscopic intraductal ultrasound (IDUS) is also a useful approach for the diagnosis of biliary malignancies. However, whether IDUS can guide the sampling by biliary brushing has not been reported.

Methods

We retrospectively analyzed patients who underwent endoscopic retrograde cholangiopancreatography for BS in 2 tertiary care hospitals and assessed the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of IDUS and brush cytology.

Results

The study involved 530 patients with BS, including 333 in the IDUS group and 197 in the non-IDUS group. Both

SUBMITTER: Wang J 

PROVIDER: S-EPMC11928891 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature