Is segmentectomy potentially adequate for clinical stage IA3 non-small cell lung cancer.

ABSTRACT:

Objectives

This study aims to identify the feasibility of segmentectomy for clinical stage IA3 (cIA3) vs cIA1-2 non-small cell lung cancer (NSCLC).

Methods

We retrospectively analysed data of consecutive patients with segmentectomy for cIA NSCLC across three centres between January 2017 and December 2022. The stabilized inverse probability of treatment-weighting (IPTW) was employed to minimize potential confounding in baseline characteristics. Recurrence-free survival (RFS) differences were examined using Kaplan-Meier estimator with the log-rank test. The Cox regression model was applied to assess the average treatment effect (ATE) between two groups in RFS. Subgroup and sensitivity analyses were performed.

Results

Of a total of 589 patients who underwent segmentectom

SUBMITTER: Huang L 

PROVIDER: S-EPMC11928928 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature