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Comparative analysis of necrotizing enterocolitis in preterm infants born in Japan and born to mothers of Japanese ethnicity in California.


ABSTRACT: Infants born in Japan are reported to have a low incidence of necrotizing enterocolitis (NEC) among countries, and these differences remained significant after adjusting for common clinical factors. To investigate the impact of ethnic background, we compared the incidence of NEC between infants born in Japan and those born to mothers of Japanese ethnicity in California. Preterm infants born between 2008 and 2019 at 22-29 weeks of gestational age were analyzed retrospectively. Four groups were analyzed: infants born in Japan (JP), infants born in California to mothers born in Japan (JP-J), infants born in California to mothers with Japanese ethnicity but born in the United States or another country (JP-CA), and a comparison group of infants born in California to non-Hispanic White mothers (

SUBMITTER: Kusuda S 

PROVIDER: S-EPMC11929812 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature