Machine learning-based prediction of vesicoureteral reflux outcomes in infants under antibiotic prophylaxis.

ABSTRACT: We aimed to investigate the independent outcome predictors of continuous antibiotic prophylaxis (CAP) in vesicoureteral reflux, train a model to predict the outcome, and evaluate which infants should be referred for endoscopic vesicoureteral reflux correction in their first visits. A total of 225 infants ≤ 2 years of age with a diagnosis of vesicoureteral reflux between 2009 and 2022 were recruited; 115 patients from a pediatric nephrology clinic received CAP, and 110 patients from a pediatric urology department underwent endoscopic injection of dextranomer/hyaluronic acid copolymer. In the multivariable analysis, only renal scarring and bladder dysfunction were significantly associated with post-treatment febrile urinary tract infections and/or renal scarring and vesicoureteral reflux per

SUBMITTER: Tafazoli N 

PROVIDER: S-EPMC11929824 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature