Trends in mortality due to ischemic heart diseases among patients with Alzheimer's disease in the United States from 1999 to 2020.

ABSTRACT:

Background

Ischemic heart diseases (IHD) and Alzheimer's Disease (AD) significantly contribute to mortality in aging population. Understanding mortality trends where these conditions overlap is crucial for developing targeted interventions for vulnerable populations.

Methods

We analyzed CDC WONDER mortality data from 1999 to 2020 for individuals aged ≥45 years. IHD and AD mortality were identified using ICD-10 codes I20-I25 and G30, respectively. Age-adjusted mortality rates (AAMR) per 100,000 were calculated, and trends were analyzed by gender, race, region, place of death and state. Joinpoint regression was used to calculate annual percentage changes (APC) with 95 % confidence intervals (CI).

Results

A total of 171,080 deaths were attributed to IHD in individuals wi

SUBMITTER: Akhtar M 

PROVIDER: S-EPMC11929933 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature