The global burden and biomarkers of cardiovascular disease attributable to ambient particulate matter pollution.

ABSTRACT:

Background

Understanding the evolving patterns of cardiovascular disease (CVD) burden attributable to ambient particulate matter pollution (APMP) is essential. Furthermore, research on the underlying mechanisms has mostly been limited to laboratory and animal models, with few large-scale population-based studies.

Methods

Using data from the Global Burden of Disease Study (GBD) 2021, we analyzed disability-adjusted life years and mortality for CVD attributable to APMP (measured as particulate matter [PM]_2.5) from 1990 to 2021. We examined shifts in burden between APMP and household air pollution (HAP), regional disparities by socio-demographic index (SDI), and predicted trends using a Bayesian age-period-cohort model. Additionally, we used UK Biobank (UKB) data (me

SUBMITTER: Tang H 

PROVIDER: S-EPMC11930010 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature