Associations Among Circle-Based Kidney Allocation, Center Waiting Time, and Likelihood of Deceased-Donor Kidney Transplantation.

ABSTRACT:

Rationale & objective

The kidney allocation system (KAS250), using circle-based distribution, attempts to address geographic disparities through broader sharing of deceased-donor kidney allografts. This study evaluated the association between KAS250 and likelihood of deceased-donor kidney transplantation (DDKT) among wait-listed candidates, and whether the policy has differentially affected centers with shorter versus longer waiting time.

Study design

Retrospective cohort study.

Setting & participants

160,941 candidates waitlisted at 176 transplant centers between March 2017 and March 2024.

Exposure

KAS250 allocation policy.

Outcome

Rate of DDKT.

Analytical approach

Multivariable Cox regression, modeling KAS250 as a time-dependent variable.

Res

SUBMITTER: Cron DC 

PROVIDER: S-EPMC11930355 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature