Identifiable Historic and Observable Factors May Predict Progression to Exfoliation Glaucoma in Newly Diagnosed Exfoliation Patients.

ABSTRACT:

Objective

To identify clinical factors associated with conversion to exfoliation glaucoma (XFG) in exfoliation syndrome (XFS) patients who are most at risk of progression to XFG within 3 years for increased surveillance and early preventive interventions.

Design

A retrospective patient cohort study design was employed.

Subjects

A source population of XFS patients ≥ 50 years was identified from electronic medical records in the Utah Population Database. From this, 487 study patients with one or more dilated eye examinations before chart-confirmed XFS onset in 2011 or later and ≥ 3 years of subsequent eye examinations were selected for study.

Methods

We implemented binomial linear mixed models with L1-penalized estimation to select variables associated with conve

SUBMITTER: Curtin K 

PROVIDER: S-EPMC11930615 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature