Understanding Discontinuation Rates and Acceptance of the Low-Dose Levonorgestrel Intrauterine System in Spain: A Comprehensive Analysis of Bleeding Patterns and Influencing Factors.

ABSTRACT:

Purpose

To estimate the 1-year continuation rate of low-dose levonorgestrel-releasing intrauterine systems (LNG-IUS) in Spanish women and elucidate potential factors impacting continuation.

Materials and methods

A prospective, multicenter, noninterventional study with a 1-year follow-up was conducted in Spain. Participants were 18-35-year-old women using low-dose LNG-IUS. Clinical and demographic data were collected, and the association between baseline characteristics and discontinuation rate was analyzed.

Results

A total of 289 women (9.3% using 13.5 mg LNG-IUS and 90.6% using 19.5 mg LNG-IUS) completed the study, and 9% discontinued prematurely after 12 months. A statistically significant association was found between LNG-IUS discontinuation and educational level (

SUBMITTER: Perello-Capo J 

PROVIDER: S-EPMC11931107 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature