Hotspots and frontiers in patent foramen ovale research: a bibliometric and visualization analysis from 2003 to 2023.

ABSTRACT:

Background

Patent foramen ovale (PFO) is among the most common congenital heart defects. Over the last two decades, the number of research publications on PFO has increased. This study aims to identify and describe the current state, hotspots, and emerging trends in PFO research over the previous 20 years using bibliometric analysis and visual mapping.

Methods

The Web of Science Core Collection was searched for all publications on PFO research, which were then included in the study. CtieSpace, VOSviewer, and Excel software were used to visualize general information, publication output, countries/regions, authors, journals, influential papers, and keyword trends in this field.

Results

This comprehensive analysis included 14,495 publications from 6,190 institutions acro

SUBMITTER: He Y 

PROVIDER: S-EPMC11931168 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature