Brain Networks Differ According to Levels of Interference in Spatiotemporal Processing.

ABSTRACT: The ability to form different neural representations for similar inputs is a central process of episodic memory. Although the dorsal dentate gyrus and CA3 have been indicated as important in this phenomenon, the neuronal circuits underlying spatiotemporal memory processing with different levels of spatial similarity are still elusive. In this study, we measured the expression of the immediate early gene c-Fos to evaluate brain areas activated when rats recalled the temporal order of object locations in a task, with either high or low levels of spatial interference. Animals showed spatiotemporal memory in both conditions once they spent more time exploring the older object locations relative to the more recent ones. We found no difference in the levels of c-Fos expression between high and l

SUBMITTER: Castelo-Branco R 

PROVIDER: S-EPMC11931270 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature