Electrokinetic Motion of Neurotransmitter Ions through a 1.01 nm Diameter Single-Walled Carbon Nanotube.

ABSTRACT: The transport of cations of the neurotransmitters acetylcholine, choline, and dopamine through a 1.01 nm-diameter, 1.1 mm-long single-walled carbon nanotube (SWNT) has been studied for the first time. As a comparison, sodium and aniline ion transport was also investigated. All of these ions exhibited significantly enhanced electrophoretic mobilities over bulk transport. The electrophoretic mobilities of acetylcholine, choline, and sodium were found to depend on pH, specifically increasing as pH decreases. This result is explained by hydrogen ions saturating the surface charges of the SWNT. Conversely, dopamine and aniline have mobilities that do not depend on pH. This difference is attributed to the benzene ring and the size of these ions. An analysis of the time required for an ion to tra

SUBMITTER: Ellison MD 

PROVIDER: S-EPMC11931543 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature