Urinary Metabolomics of Plastic Manufacturing Workers: A Pilot Study.

ABSTRACT: The plastic manufacturing industry has a crucial role in the global economy with a significant impact in a wide range of fields. The chemical risk to which workers are potentially exposed is difficult to characterize and strictly related to both the products and processes adopted. Among the chemicals used, we can cite styrene, phenol, butadiene and phthalates, but nano- and microplastic particles can also be released in the work environment. In this pilot study, we present for the first time an NMR-based metabolomic approach for assessing urinary profiles of workers employed in a plastic manufacturing company. Urine samples from twelve workers and thirteen healthy volunteers were collected and analyzed by NMR spectroscopy. Forty-six urinary metabolites belonging to different chemical class

SUBMITTER: De Rosa M 

PROVIDER: S-EPMC11932285 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature