Decompressive Nerve Surgery Associated with Low Diabetic Foot Ulcer Rate and High-Risk Bias: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Diabetic sensorimotor polyneuropathy (DSPN) occurs in 50% of patients with diabetes mellitus (DM). Up to 70% of DM patients incur diabetic foot ulcers (DFUs). Of those with DSPN, 20% develop DFUs. Decompression nerve surgery (DNS) purportedly improves DSPN and DFU. As there is no accurate, pooled DFU incidence following DNS, the authors performed a systematic review and meta-analysis of DFU incidence following DNS. Given the 60% global DFU incidence, they hypothesized a lower, pooled DFU incidence following DNS.

Methods

Two authors searched 6 databases from database inception to July of 2023 for DNS clinical studies. Primary tracked outcomes were new and recurrent DFU incidence following DNS. Included studies were clinical studies of adult patients with DM, DNS of

SUBMITTER: Louca M 

PROVIDER: S-EPMC11932444 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature