Intrahepatic cholestasis of pregnancy and gestational diabetes: Protocol for a scoping review of associations, risk factors, and outcomes.

ABSTRACT:

Background

Intrahepatic cholestasis of pregnancy (IHCP) is a pregnancy-related liver disease associated with adverse pregnancy outcomes, including spontaneous preterm labour, fetal hypoxia, meconium-stained liquor and intrauterine death. In women with IHCP, comorbidities may be associated with a greater risk of stillbirth. Recent studies have suggested that cholestasis of pregnancy may be associated with Gestational Diabetes Mellitus (GDM).

Objective

This scoping review aims to comprehensively investigate the nature and strength of the association between Intrahepatic Cholestasis of Pregnancy (IHCP) and Gestational Diabetes Mellitus (GDM). The review also seeks to identify common risk factors contributing to the association and explore potential adverse effects associated wi

SUBMITTER: Abubakr K 

PROVIDER: S-EPMC11932483 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature