Biomarkers associated with cognitive impairment in post-traumatic stress disorder: A systematic review of current evidence.

ABSTRACT:

Objective

This systematic review aimed at synthesizing current evidence on biomarkers associated with cognitive impairment (CI) in Post-Traumatic Stress Disorder (PTSD).

Methods

A systematic literature search was conducted for studies assessing biomarkers associated with CI in PTSD.

Results

Of the 10,149 titles screened, 8 studies met our inclusion criteria. In a single longitudinal study, MRI volumes, Aβ and tau accumulation were not associated with CI in PTSD. Studies on structural imaging reported no significant association between morphological changes and CI. Two studies on diffusion neuroimaging showed abnormalities in white matter tracts which were cross-sectionally associated with CI in PTSD. Similarly, lower resting-state functional connectivity in neocortica

SUBMITTER: Guo J 

PROVIDER: S-EPMC11932974 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature