Interictal waking and sleep electrophysiological properties of the thalamus in focal epilepsies.

ABSTRACT: Epilepsy is a cortico-subcortical network disease. Thalamo-cortical relationships in focal epilepsies, studied by stereoelectroencephalography in complex patients during pre-surgical evaluation, might help refine epilepsy surgery prognostic indicators and patient-specific treatments (i.e. thalamic deep brain stimulation). To this aim, we studied interictal thalamic traces, during rest and sleep recordings, in a cohort of 121 patients, delving into thalamo-cortical connectivity, hyperexcitability biomarkers and their correlation with treatment outcome. We retrospectively gathered stereoelectroencephalography recordings and clinical variables from patients who underwent stereoelectroencephalography with mainly a posterior-thalamic implantation, aiming at the pulvinar. Interictal recordings d

SUBMITTER: Biagioni T 

PROVIDER: S-EPMC11934066 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature