Genomic analysis of multidrug-resistant <i>Escherichia coli</i> isolated from dairy cows in Shihezi city, Xinjiang, China.

ABSTRACT:

Introduction

Dairy farming plays a vital role in agriculture and nutrition; however, the emergence of antimicrobial resistance (AMR) among bacterial pathogens poses significant risks to public health and animal welfare. Multidrug-resistant (MDR) Escherichia coli strains are of particular concern due to their potential for zoonotic transmission and resistance to multiple antibiotics. In this study, we investigated the prevalence of AMR and analyzed the genomes of two MDR E. coli isolated from dairy cows in Shihezi City.

Methods

Fecal samples were collected from dairy cows, and E. coli strains were isolated. Antibiotic susceptibility testing was conducted using the Kirby-Bauer disk diffusion method against 14 antibiotics. Two MDR isolates (E.coli_30 and E.

SUBMITTER: Bello A 

PROVIDER: S-EPMC11934113 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature