Long-term prognostic value of thyroid hormone levels in chronic critical illness patients.

ABSTRACT:

Background

Chronic critical illness (CCI) can manifest as dysfunction of thyroid hormones. This study aimed to investigate the predictive value of the nonthyroidal illness syndrome (NTIS) for the prognosis of CCI patients, establish a predictive model for the prognosis of CCI patients, and evaluate the efficacy of the model to provide a theoretical basis for clinical intervention.

Methods

This was a prospective observational study in which patients ≥18 years old who met the CCI criteria were enrolled. The primary outcome of the study was 90-day mortality after intensive care unit (ICU) admission. A nomogram was constructed to predict the prognosis of CCI patients, and the model was evaluated via the concordance index, calibration curve and decision curve analysis.

Results

SUBMITTER: Li Z 

PROVIDER: S-EPMC11934158 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature