Assessment of dietary, genetic and metabolic factors in South Indian adolescents with metabolic dysfunction-associated steatotic liver disease: a case-control study protocol.

ABSTRACT:

Introduction

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading cause of liver disease among adolescents. The objectives of this study are to investigate the associations of dietary, genetic and metabolic factors with MASLD in South Indian adolescents.

Methods and analysis

The study will employ a case-control study design. We will recruit 280 adolescents (140 cases and 140 controls) from hospital and school settings. The hospital setting will be the paediatric gastroenterology outpatient department (OPD) at the study institution and the school setting will be selected urban schools from Ernakulam, Kerala. At the hospital, cases and controls will be selected from the patients who are attending the paediatric gastroenterology OPD with complaints of g

SUBMITTER: Venu S 

PROVIDER: S-EPMC11934355 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature