Sex-specific associations of serum short-chain fatty acids with glycaemic control: an Italian cross-sectional study in adults with type 1 diabetes.

ABSTRACT:

Objective

Short-chain fatty acids (SCFA) play a role in modulating glucose metabolism and are influenced by diet. Alterations in the SCFA-producing microbial ecosystem in individuals with type 1 diabetes (T1D) may contribute to impaired glycaemic control. This study investigated the relationships between serum SCFA levels, blood glucose control, and dietary habits in adults with T1D.

Design

Observational study.

Setting

The study was conducted at the diabetes outpatient clinic of Federico II University Teaching Hospital, Naples, Italy.

Population

The study included 198 adults with T1D (100 men and 98 women), aged 18-79 years.

Main outcome measures

Serum SCFA levels, blood glucose control, assessed by glycated haemoglobin (HbA1c) and continuous glucose mon

SUBMITTER: Abuqwider J 

PROVIDER: S-EPMC11934402 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature