Association of hemoglobin-to-red blood cell distribution width ratio with mortality in critically Ill patients with heart failure and acute kidney injury: insights from the MIMIC-IV database.

ABSTRACT:

Background

The association between the hemoglobin-to-red cell distribution width ratio (HRR) and mortality in critically ill patients with heart failure (HF) and acute kidney injury (AKI) remains uncertain. This research focuses on exploring the association between HRR and both short-term and long-term all-cause mortality in these patients.

Methods

Participants were selected from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database and categorized into tertiles based on HRR values. The primary endpoint was 28-days ICU all-cause mortality. Secondary endpoints included 28-days hospital and 90-days hospital all-cause mortality. Cox proportional hazards models and restricted cubic splines were used to analyze the association between HRR and mortality in patient

SUBMITTER: Xu X 

PROVIDER: S-EPMC11934673 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature