Dip-Pen Nanolithography-Based Fabrication of Meta-Chemical Surface for Heavy Metal Detection: Role of Poly-Methyl Methacrylate in Sensor Sensitivity.

ABSTRACT: A meta-chemical surface is being patterned via dip-pen nanolithography (DPN) for novel electrochemical heavy metal sensors. The unique feature of DPN allows a precise transfer of desired ink onto various surfaces. Two kinds of sensors are being developed, which differ by the ligand in the poly-methyl methacrylate (PMMA)-based ink: 1,8-diaminonaphthalene (DAN) and D-penicillamine (D-PA). The nanosize, the surface-to-volume ratio (18.6 and 23.1 μm^-1 for DAN- and D-PA-based ink, respectively), and the binding strength between the ligand and the cation (2.21 and -21.37 kcal mol^-1 for DAN- and D-PA-based ink, respectively) are found to be the source of their high sensitivity, with limit of detection values of 0.40 and 0.30 ppb for DAN and D-PA, respectively. According to t

SUBMITTER: Okbi R 

PROVIDER: S-EPMC11934891 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature