IPANEMAP Suite: a pipeline for probing-informed RNA structure modeling.

ABSTRACT: In addition to their sequence, multiple functions of RNAs are encoded within their structure, which is often difficult to solve using physico-chemical methods. Incorporating low-resolution experimental data such as chemical probing into computational prediction significantly enhances RNA structure modeling accuracy. While medium- and high-throughput RNA structure probing techniques are widely accessible, the subsequent analysis process can be cumbersome, involving multiple software and manual data manipulation. In addition, the relevant interpretation of the data requires proper parameterization of the software and a strict consistency in the analysis pipeline. To streamline such workflows, we introduce IPANEMAP Suite, a comprehensive platform that guides users from chemically probing raw

SUBMITTER: Hardouin P 

PROVIDER: S-EPMC11934922 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature