Treatment and survival of non-metastatic rectal cancer in patients with inflammatory bowel disease: nationwide cohort study.

ABSTRACT:

Background

Patients with inflammatory bowel disease have an increased risk of colorectal cancer. There is a scarcity of large studies with a focus on rectal cancer in patients with inflammatory bowel disease. This study aimed to compare survival in resected patients with rectal cancer with and without inflammatory bowel disease.

Methods

This national population-based study used the Colorectal Cancer Data Base. All Swedish patients ≥18 years of age with a diagnosis of stage I-III rectal cancer between 1997 and 2021, surgically treated with curative intent, were included and followed up until 2022. The outcome of interest was recurrence-free survival. Flexible parametric survival models adjusted for time since surgery, year of diagnosis, sex, age at diagnosis, and Charlson Co-

SUBMITTER: Lundqvist E 

PROVIDER: S-EPMC11934924 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature