A Novel DNA-Based Dual-Mode Data Storage System with Interrelated Concise and Detailed Data.

ABSTRACT: DNA has emerged as a promising storage medium to meet the soaring need for archival data storage because of its exceptional storage density and stability. However, current DNA-based data storage systems are incompetent of achieving high-quality random multiplexed access and frequently accessed data storage, which impedes its practical applications. Here, a dual-mode storage system is proposed that combines DNA-based archival data and nanodot-based active data. This novel data-storage system is constructed by writing the active and archival data on the same substrate through a facile two-step process involving scanning probe lithography (SPL), DNA synthesis, and chemical immobilization. The data files are categorized and stored orderly in different microregions of the substrate to achieve e

SUBMITTER: Pei B 

PROVIDER: S-EPMC11935158 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature