Integrated Microfluidics for Single-Cell Separation and On-Chip Analysis: Novel Applications and Recent Advances.

ABSTRACT: From deciphering infection and disease mechanisms to identifying novel biomarkers and personalizing treatments, the characteristics of individual cells can provide significant insights into a variety of biological processes and facilitate decision-making in biomedical environments. Conventional single-cell analysis methods are limited in terms of cost, contamination risks, sample volumes, analysis times, throughput, sensitivity, and selectivity. Although microfluidic approaches have been suggested as a low-cost, information-rich, and high-throughput alternative to conventional single-cell isolation and analysis methods, limitations such as necessary off-chip sample pre- and post-processing as well as systems designed for individual workflows have restricted their applications. In this revi

SUBMITTER: Kutluk H 

PROVIDER: S-EPMC11935165 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature