Generation of Pulsatile Flow using Clinical Continuous Flow Pumps.

ABSTRACT:

Background

With the increasing use of mechanical circulatory support for long-term augmentation of cardiopulmonary function, the need for safer devices is apparent. Pump thrombosis and failure, inadequate ventricular unloading, progressive right-sided dysfunction, and end-organ hypoperfusion are seen with long-term mechanical circulatory support devices. Generation of pulsatile flow has been proposed to mitigate some of these risks by providing physiologic flow and pressure profiles to the vascular system and end-organs. Modification of continuous flow devices to provide pulsatility may prove a cheap and effective way to achieve physiologic flow; however, effective use of such a technique has yet to be demonstrated. This work aims to describe these efforts, as well as mechanical ar

SUBMITTER: Birjiniuk J 

PROVIDER: S-EPMC11935380 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature