The impact of donor-recipient age difference on graft survival after heart transplant in adults with congenital heart disease.

ABSTRACT:

Background

The impact of donor-recipient age difference in adult congenital heart disease (ACHD) patients undergoing heart transplant (HT) is unknown.

Methods

ACHD patients (≥18 years old) who underwent HT (2000-2020) were identified using the United Network for Organ Sharing database. Graft survival through 10 years based on donor-recipient age difference was evaluated by comparing outcomes of donors >5 years older than recipients (Older), donors within 5 years of recipient age (Equal Age), and donors >5 years younger than recipients (Younger, reference group). Cox multivariable analysis was performed to evaluate the effect of donor-recipient age difference on early and late graft survival.

Results

A total of 1,275 ACHD patients underwent HT (60% male, median 35 year

SUBMITTER: Marshall WH 

PROVIDER: S-EPMC11935387 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature