Fungal colonization before or after lung transplantation has no negative impact on survival or the development of chronic lung allograft dysfunction.

ABSTRACT:

Introduction

Long-term survival following lung transplantation (LTx) faces impediments due to chronic lung allograft dysfunction (CLAD), while infections hinder short-term survival. Fungal colonization and invasive fungal infections (IFI) are common within the first year after LTx. There is ongoing debate regarding the impact of such events on CLAD development and mortality. This study aims to investigate this matter further.

Methods

A total of 134 LTx recipients transplanted between 2011 and 2020 were included. The median follow-up time was 3.9 years. Fungal colonization and IFI were defined according to international consensus guidelines and were noted if present within the first 12 months after LTx.

Results

Postoperative fungal colonization was found in 101 patient

SUBMITTER: Boden E 

PROVIDER: S-EPMC11935453 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature