Association of diuretic requirement and right heart failure post-LVAD implantation.

ABSTRACT:

Background

Diuretic responsiveness is associated with heart failure disease progression. Among patients with advanced heart failure, we hypothesized that decreased diuretic responsiveness and higher diuretic requirement are correlates of progressive right ventricular dysfunction and may help to risk stratify patients undergoing left ventricular assist device (LVAD) evaluation.

Methods

We performed a single-center, retrospective analysis of 147 patients undergoing LVAD implantation between 2014 and 2018. The primary outcome was early right heart failure (RHF) or death during the index hospital stay. Patients were stratified by tertiles of preoperative 24-hour diuretic dose within 72 hours of surgery.

Results

The incidence of early RHF was higher in the highest-dose gro

SUBMITTER: Huang D 

PROVIDER: S-EPMC11935456 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature