Exercise capacity and cardiac allograft ischemic time in recent heart transplant recipients.

ABSTRACT:

Background

Prolonged ischemic times (IT) for transplant hearts transported under cold storage conditions are associated with an increased risk of mortality; however, the impact of IT on functional outcomes, such as exercise capacity (EC), is not fully understood. This prospective, observational cohort study aimed to determine the association between EC, a strong predictor for post-transplant survival, and relatively longer IT.

Methods

Thirty heart transplant recipients were grouped dichotomously according to relatively longer (>180 minutes) or shorter (≤180 minutes) IT. A cardiopulmonary exercise test (CPET) was performed post-transplant upon cardiac rehabilitation admission, during which EC [peak volume of oxygen consumption (VO₂)] and CPET duration were measured

SUBMITTER: Bosteder KD 

PROVIDER: S-EPMC11935468 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature