A multicenter analysis of lung transplantation outcomes comparing donation after circulatory death and donation after brain death.

ABSTRACT:

Background

Donor organ shortage is a barrier to lung transplantation. Donation after circulatory death (DCD) may offer a solution, although it is underutilized. The objective of this study was to compare survival and other postoperative outcomes between DCD and donation after brain death (DBD).

Methods

We performed a multicenter analysis of Multi-Institutional Extracorporeal Life Support (ECLS) Registry data from 11 lung transplant centers in the United States and Europe. Demographics and clinical parameters were compared using chi-square test and Fisher's exact test. Survival was assessed by Kaplan-Meier curves and compared by log-rank test with propensity score matching.

Results

Of 1,585 patients included in the study, 135 (8.5%) received DCD lungs and 1,450 (91.5%)

SUBMITTER: Abul Kashem M 

PROVIDER: S-EPMC11935477 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature