Trajectories of postoperative serum troponin concentrations following pediatric heart transplantation.

ABSTRACT:

Background

Troponin is a biomarker of myocardial injury and death but has not been well studied after pediatric heart transplants. The objective of this analysis is to describe the distribution and clinical determinants of serum troponin measured in the first week after pediatric heart transplantation.

Methods

We included all patients who underwent heart transplantation at Seattle Children's Hospital between 2012 and 2016. Serum Troponin-I (TnI) was measured daily in the first week after transplant. We described the distribution of serum TnI, and examined the relationship between peak TnI with known pre- peri-operative risk factors for myocardial injury including etiology of heart failure, ischemia time, and donor to recipient characteristics. Logistic regression models were

SUBMITTER: Kula AJ 

PROVIDER: S-EPMC11935518 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature