Outcomes of combined liver-lung transplant in pediatric patients with cystic fibrosis: An ISHLT transplant registry study.

ABSTRACT:

Background

Concomitant liver and lung transplant (ConLi-LTx) may be indicated for select pediatric patients with cystic fibrosis (CF). This study aims to analyze pre-transplant predictors and post-transplant outcomes of ConLi-LTx and lung transplant (LTx) only in pediatric patients with cystic fibrosis.

Methods

The ISHLT International Thoracic Organ Transplant Registry was queried for patients <18 years old with CF who underwent ConLi-LTx and LTx-only from 1994-June 2018. Data were propensity matched to LTx-only controls and analyzed with Fisher's exact, Wilcoxon rank sum tests, Kaplan-Meier methods, and Cox proportional hazards where appropriate.

Results

We identified 18 ConLi-LTx who were compared to 72 LTx-only cases. No significant differences were identified in p

SUBMITTER: Wilson R 

PROVIDER: S-EPMC11935521 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature