Peak Oxygen Consumption Scaled to Body Composition Is Associated With Mortality and Morbidity in People With a Fontan Circulation.

ABSTRACT:

Background

Peak oxygen consumption (peak V̇$$ \dot{\mathrm{V}} $$O₂) is traditionally scaled by body mass, but it is most appropriately scaled by fat-free mass. However, it is unknown whether peak V̇$$ \dot{\mathrm{V}} $$O₂ scaled by fat-free mass is associated with mortality and morbidity in people with a Fontan circulation. The aim of this study was to assess the associations between different expressions of peak V̇$$ \dot{\mathrm{V}} $$O₂ with mortality and morbidity in people with a Fontan circulation.

Methods and results

Eighty-seven participants (aged 24.1±7.3 years; 53% women) with a Fontan circulation completed a cardiopulmonary exercise test and a dual-energy x-ray absorptiometry scan. Cox proportional hazard regressions models asses

SUBMITTER: Wadey CA 

PROVIDER: S-EPMC11935541 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature