Significance of an Early Repeat Troponin Measurement Upon Presentation to the Hospital for Acute Heart Failure.

ABSTRACT:

Background

Higher cardiac troponin is associated with worse outcomes in patients with acute heart failure. The significance of repeat measurements over hours remains unclear. We assessed whether a repeat measurement and the Δ between measurements of high-sensitivity cardiac troponin I (hs-cTnI) were associated with outcomes in hypervolemic patients with acute heart failure without acute coronary syndrome.

Methods and results

We analyzed 582 individuals from AKINESIS (Acute Kidney Injury Neutrophil Gelatinase-Associated Lipocalin Evaluation of Symptomatic Heart Failure Study) with hs-cTnI measured ≤12 hours from admission and repeated ≤6 hours thereafter. Associations between hs-cTnI levels and their Δ with short-term (death, intensive care unit admission, receipt of inotrope

SUBMITTER: Horiuchi Y 

PROVIDER: S-EPMC11935605 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature