Serial Optical Coherence Tomography Assessment of Coronary Atherosclerosis and Long-Term Clinical Outcomes.

ABSTRACT:

Background

The impact of high-risk coronary artery plaques identified using optical coherence tomography on late luminal narrowing and clinical events remains poorly understood.

Methods and results

This multicenter prospective study included 176 patients who underwent percutaneous coronary intervention and serial optical coherence tomography at baseline and 1-year follow-up to investigate nontarget regions with angiographically intermediate stenosis. At 1 year after percutaneous coronary intervention, the coronary artery lumen area decreased significantly from 6.06 (95% CI, 5.60-6.53) mm² to 5.88 (95% CI, 5.41-6.35) mm² (difference, -0.18; 95% CI, -0.22 to -0.14 mm²; P<0.001), particularly in thin-cap fibroatheromas, thick-cap fibroath

SUBMITTER: Yamaji K 

PROVIDER: S-EPMC11935709 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature