Longitudinal Assessment of T1 Mapping Trends Disease in Pediatric Patients With Heart Transplant.

ABSTRACT:

Background

Surveillance for heart transplant rejection by endomyocardial biopsy is invasive and may yield false negatives. T1 and T2 mapping from cardiac magnetic resonance can demonstrate elevations with rejection. We sought to evaluate longitudinal changes in T1 and T2 mapping in pediatric patients with heart transplant.

Methods and results

A cohort study was performed of pediatric patients with heart transplant who underwent concurrent endomyocardial biopsy and cardiac magnetic resonance with T1 and T2 mapping from December 2019 to July 2024. Segmental values were measured and subsegmental elevations (ie, hotspots) were identified. Subjects were categorized as either treated rejection or no rejection. Peak and mean T1 and T2 values and number of hotspots at/between each t

SUBMITTER: Ceneri NM 

PROVIDER: S-EPMC11935723 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature