Air Hunger Far Exceeds Dyspnea Sense of Effort during Mechanical Ventilation and a Weaning Trial.

ABSTRACT: Rationale: No systematic investigation into dyspnea in patients receiving prolonged ventilation (>21 d) after recovering from critical illness has been published. Objectives: We sought to determine the magnitude, nature, and pathophysiological basis of dyspnea during an unassisted-breathing trial in patients receiving prolonged ventilation. Methods: Dyspnea intensity and descriptor selection were investigated in 27 patients receiving prolonged ventilation during a 60-minute unassisted-breathing trial. Pressure-time product, respiratory mechanics, and Ptc_CO2 were also measured. Measurements and Main Results: Of 10 patients who reported dyspnea during assist-control ventilation, 9 (90.0%) selected "Not getting enough air" to characterize dysp

SUBMITTER: Jubran A 

PROVIDER: S-EPMC11936149 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature