Antimicrobial and antiparasitic potential of lupeol: antifungal effect on the <i>Candida parapsilosis</i> species complex and nematicidal activity against <i>Caenorhabditis elegans</i>.

ABSTRACT: Introduction. There is growing concern about infections caused by non-albicans Candida species, including species of the Candida parapsilosis complex - which have seen a considerable increase in cases during the COVID-19 pandemic - in addition to concern about nematode resistance to currently used anthelmintics.Gap Statement. Lupeol is a triterpenoid phytosterol that has a wide range of biological activities, although its antifungal and antiparasitic potential is still poorly explored. Additionally, its effect on the biofilm of the C. parapsilosis species complex has not yet been studied.Aim. This study aimed to investigate the antifungal effect of lupeol against C. parapsilosis complex species, in planktonic cells and mature biofilms, as we

SUBMITTER: da Silva Dutra M 

PROVIDER: S-EPMC11936342 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature