Unilateral or Bilateral Laparoscopic Ovarian Drilling in Polycystic Ovary Syndrome: A Meta-analysis of Randomized Trials.

ABSTRACT:

Objectives

On the first line of polycystic ovary syndrome (PCOS) treatment, ovulation with clomiphene citrate (CC) is induced. However, 25% of patients need alternative therapy. Laparoscopic ovarian drilling (LOD) can result in successive ovulations and is not linked to ovarian hyperstimulation. In this systematic review and meta-analysis, we aimed to consider the efficacy of unilateral LOD (ULOD) versus bilateral LOD (BLOD) for enhancing fertility and improving fertility outcomes in women with CC-resistant.

Materials and methods

A comprehensive literature search was conducted up to July 15, 2023, to identify relevant randomized controlled trials in PubMed, Scopus, Google Scholar, and Cochrane Library databases. Thirteen articles were included in the meta-analysis. After dat

SUBMITTER: Zakerinasab F 

PROVIDER: S-EPMC11936394 | biostudies-literature | 2025 Jan-Mar

REPOSITORIES: biostudies-literature