The Association Between Estrogen-Containing Oral Contraceptive Pills and Hypothyroidism.

ABSTRACT: Background: Hypothyroidism is an endocrine disorder that affects 10 times more females than males, with substantial health impacts. The role of estrogen-containing oral contraceptives (OCPs) in influencing thyroid function remains relatively underexplored. This study investigated the association between estrogen-containing OCP use and hypothyroidism in the female population in Qatar. Methods: We utilized data from the Qatar Biobank to conduct a cross-sectional study of 1001 female participants with a current or previous history of estrogen-containing OCP use. The thyroid function of the participants was evaluated via thyroid function test parameters (thyroid stimulating hormone (TSH) and free tetraiodothyronine (fT4)) as outcomes, and sex hormone-binding globulin (SHBG) level

SUBMITTER: Alkahlout L 

PROVIDER: S-EPMC11936525 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature