<i>Flammulina velutipes</i> mycorrhizae dietary fiber attenuates the development of obesity via regulating lipid metabolism in high-fat diet-induced obese mice.

ABSTRACT:

Introduction

Mounting evidence has shown that Flammulina velutipes mycorrhizae dietary fiber (Fv-DF) has the potential to significantly improve health outcomes by addressing lipid metabolic disorders. However, the mechanism underlying Fv-DF in regulating liver lipid metabolism of high-fat diet (HFD)-induced obese mice still merits to be systematically elaborated.

Methods

Herein, we conducted a comprehensive study utilizing HFD-induced C57BL/6J mice as an obesity model to investigate the impact of Fv-DF on liver lipid accumulation.

Results

The study, which included an evaluation of Fv-DF on a high-fat diet (HFD)-induced obese mice, revealed that Fv-DF supplementation can effectively decrease weight gain, improve serum lipid levels, and reduce fat deposition in a

SUBMITTER: Jia F 

PROVIDER: S-EPMC11936819 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature