Nightlife and low immunity drove transmission of SARS-CoV-2 gamma in Luxembourg, 2021.

ABSTRACT: In summer 2021, while the Delta variant was predominant in many European countries, Luxembourg experienced a large outbreak of the P.1.17.1 SARS-CoV-2 Gamma variant. This surge coincided with the introduction of digital COVID-19 certificates and eased restrictions prior to national holiday festivities. We investigated the molecular and epidemiological factors contributing to SARS-CoV-2 Gamma transmission. All laboratory SARS-CoV-2 confirmed cases were interviewed by contact tracing teams on exposures at nightlife venues, family gatherings, schools, and workplaces. Gamma sublineages were investigated through environmental wastewater surveillance, in addition to whole genome sequencing of clinical data. Infection clusters were analysed combining phylogenetic with epidemiological exposures. F

SUBMITTER: Afonso YP 

PROVIDER: S-EPMC11937271 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature